Working With Toxic Or Other Harmful Compounds - Thermos TriPlus RSH Hardware Manual

Preface
Safety Information and Warnings

Working with Toxic or other Harmful Compounds

xxii TriPlus RSH Hardware Manual
When sample vials have to undergo heating and agitation, it is important to consider the glass
quality. Use high quality glass only. Remember that depending on the application conditions,
high pressure can build up in the vial. Whenever a temperature greater than 60 °C is applied,
consider the vapor pressure of the solvent used to ensure that no excessive pressure builds up.
This is important when using a temperature above 100°C and especially at the maximum
temperature of 200 °C. Be aware that solid materials can also contain volatile compounds
such as water (humidity) which could cause build-up of excess vapor pressure.
Do not reuse headspace vials. During the process of washing the vial, micro-cracks can form
which will weaken the glass wall and increase the chances of the vial breaking.
In case of a single fault situation where the temperature control of the Agitator fails, there is
the potential danger that the device will heat up in an uncontrolled manner until it reaches
the cut-off temperature of the over temperature fuse, in this case, 240 °C. Based on this single
fault scenario, when working with flammable solvents, ensure that the solvent used has a flash
point which is 25 °C higher than the maximum potential temperature (240 °C) of the
Agitator.
When filling-up a standard reservoir or replacing a solvent such as a washing solvent, remove
the solvent reservoir bottle from the system to avoid a possible spill over the instrument.
Depending on the physical, chemical or hazardous properties of the solvent, use the
appropriate protective measures for handling.
WARNING Before using hazardous substances (toxic, harmful, and so on), please read the
hazard indications and information reported in the applicable Material Safety Data Sheet
(MSDS). Use personal protective equipment according to the safety requirements.
Before using dangerous substances (toxic, harmful, and so on) read the hazard indications and
information reported in the Material Safety Data Sheet (MSDS) supplied by the
manufacturer, referring to the relevant CAS (Chemical Abstract Service) number. The TriPlus
RSH requires the use of several chemical products with different hazard characteristics, which
are present in vials and syringes. Before using these substances or replacing the syringe, please
read the hazard indications and information reported in the MSDS supplied by the
manufacturer referring to the relevant CAS number.
When preparing the samples, please refer to local regulations for the ventilation conditions of
the work room.
All waste materials must be collected and eliminated in compliance with the local regulations
and directives in the country where the instrument is used.
Thermo Scientific