Agilent Technologies 1290 Infinity II 2D-LC User Manual page 39

2 Concepts of 2D-LC
Active Solvent Modulation (ASM)
Figure 21
Once the ASM phase has finished, which is a settable method parameter, the
analytical gradient starts. As opposed to a dilution with a permanent by-pass, the
ASM capillary is no longer in the flow path, such that fast
possible through the sample loop only.
2D-LC User Guide
Operating principle with sample loop flow path
2
D gradients are
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