Agilent Technologies 1290 Infinity II 2D-LC User Manual page 182

6 Method Parameters
Additional Information
Example of a Dynamic Peak Parking Setup
Figure 98
Table 11
Peak-based start:
Peak-based end:
Expected time:
The maximum shift of the IRTS is 0.57 min. This means the end of peak-based
area is at 2.80 min and the next time-based cut with reference to IRTS can be
placed at 2.8 + 0.57 = 3.37 min.
If a time-based cut shifts to the front and would enter the peak-based area
NOTE
(bracket) the dynamic cut shift will not work.
Here is an example of how fluctuations that occur during a run can be
compensated with the help of the IRTS and dynamic cut shifting.
The chromatograms below shows the results obtained from MassHunter Qual.
The top 1D chromatogram shows the original reference chromatogram the
method was based on. The middle 1D chromatogram indicates the RT shift.
The cut-markers image below show that time-based cuts were dynamically
shifted accordingly.
2D-LC User Guide
Example picture of the dynamic cut shift setup
IRTS
2.10 min
2.80 min
2.67 min
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