Results; Limitations Of The Procedure; Expected Values - Siemens ADVIA 2120 Operator's Manual

Results

The system automatically performs all calculations necessary for obtaining final
results.
Through the use of complex flagging algorithms, laboratory personnel are alerted
to suspected abnormal conditions. These conditions are indicated by the
appropriate flag (such as *, +, and/or color highlighting). Whenever flags occur,
the user should review the results and take appropriate action.

Limitations of the Procedure

The limitations of the procedure are as listed:
1. When assaying samples with extremely elevated counts, the reticulocyte
method may give reticulocyte counts that differ significantly from NCCLS
manual counts. Extremely elevated counts are often seen in samples that
contain sickled cells or nucleated RBCs.
2. Samples from patients having the following cell types or conditions may
interfere with the ADVIA 120 Reticulocyte method:
Malarial parasites
Pappenheimer Bodies
Howell-Jolly Bodies
Heinz Bodies
Inclusions that give rise to basophilic stipling
Macrothrombocytes (giant platelets)
Megaloblastic anemia
Other rare, poorly characterized red cell anomalies

Expected Values

The range of expected values can vary depending on age, sex, diet, and location.
It is recommended that each laboratory establish its own range of expected
values.
The following range of expected values is based upon the duplicate assay of 60
whole blood specimens obtained from an adult population of assumed healthy
individuals.
Parameter
#RETIC (
%RETIC
CHr (pg)
9-60
Low Value
9
/L) 40
10
0.8
24
High Value
79
2.1
36
Regulatory Information