Waste Disposal Requirements; Waste Analysis - Siemens ADVIA 2120 Operator's Manual

Siemens products do not make diagnoses on patients. Siemens intends its
diagnostic products (systems, reagents, software, hardware) to be used to collect
data reflecting the patient's chemical, hematological, or immunological status at
a certain point in time. Such data must be used in conjunction with other
diagnostic information and with the attending physician's evaluation of the
patient's condition to arrive at a diagnosis and a clinical course of treatment.
Any malfunction of a Siemens diagnostic product (for example, failure to meet a
performance specification or to perform as intended) should be appropriately
addressed by laboratory personnel. Various sections of the Product Labeling
address malfunctions and their possible effect on results.

Waste Disposal Requirements

Laws and regulations enacted to protect the environment and to encourage
resource conservation require the disposal of hazardous and biohazardous wastes
in a specified manner. Some of the wastes from the ADVIA 2120/2120i
Hematology System can be classified as hazardous or biohazardous wastes. It is
essential that the laboratory take appropriate steps to determine the laws and
regulations applicable to their disposal and to effect compliance. If it is necessary
to sample instrument effluent in order to evaluate compliance with applicable
regulations, the laboratory should contact a local licensed biohazardous waste
disposal firm for assistance.
The principal wastes associated with the use of the ADVIA 2120/2120i
Hematology system are reagent containers, sample containers, system waste, and
customer-replaceable system components. All ADVIA 2120/2120i reagent
containers are manufactured of recyclable high-density polyethylene.
Sample containers with human specimens, control materials, and all reagents,
should also be handled and disposed of in accordance with the prevailing
regulations and guidelines of agencies with jurisdiction over the laboratory. Refer
to the product label and to Material Safety Data Sheets for details concerning any
special precautions related to the handling of reagents. Material Safety Data
Sheets are available from Siemens.

Waste Analysis

After running the prescribed daily wash procedure and emptying the waste
container, waste was collected from an ADVIA 2120/2120i Hematology System
operating in three analytical modes: CBC, CBC/diff, and CBC/diff/retic. Using
the autosampler, 300 CBC analytical cycles were run on fresh, whole blood
samples, followed by the daily wash cycle. The waste was thoroughly mixed and
samples were sent for analysis. The process was repeated for both the CBC/diff
and CBC/diff/retic analytical modes. All analysis, with the exception of dimethyl
formamide (DMF) was done by Tel Labs, Blessington, Ireland.
NOTE: For waste management purposes, the system generates approximately
23 mL of waste during a typical CBC/diff/retic cycle, including
SHEATH/RINSE.
Concentrations are mg/L (ppm) unless otherwise noted.
9-10 Regulatory Information