Fresenius Medical Care 2008K Operator's Manual page 63

Final Dialysate Composition
Final Dialysate contains sodium, bicarbonate, and the minor dialysate constituents shown on
the "Dialysate" screen. The 2008K hemodialysis machine maintains dialysate sodium and
bicarbonate at the prescribed levels using a volumetric proportioning system. The
conductivity of the dialysate is displayed and used to monitor, but not control, the Final
Dialysate composition.
The dialysate constituents depend on the sodium and bicarbonate selections; they will change
if either the sodium or bicarbonate selection changes. When the operator changes the
prescribed bicarbonate (set in the Bicarbonate button), the acid stream also changes in order
to keep the prescribed Final Dialysate sodium constant. Similarly, when the operator changes
the prescribed sodium (set in the Base Na+ button), the bicarbonate stream also changes in
order to keep the prescribed Final Dialysate bicarbonate level constant.
The minor electrolyte constituents of potassium, calcium, and magnesium are part of the acid
stream and will change from nominal settings when the bicarbonate or sodium is changed
from nominal. For the NaturaLyte, GranuFlo, and Citrasate® brand concentrates, Table 11
provides examples of how potassium, calcium, and magnesium are affected as the prescribed
sodium changes, first from the nominal 137 mEq/L to the lowest limit of 130 mEq/L and then
the highest limit of 155 mEq/L. These changes to the dialysate composition keep the
prescribed Final Dialysate bicarbonate level constant.
Table 11 – Final Dialysate Ranges in mEq/L with Bicarbonate Constant at 33 mEq/L
Prescribed
Sodium
Sodium
137 mEq/L
137
nominal setting
130 mEq/L
130
lowest setting
155 mEq/L
155
highest setting
GranuFlo 2251-3B with 8 mEq/L Acetate (4 mEq/L Acetic Acid + 4 mEq/L Sodium Acetate)
Prescribed
Sodium
Sodium
137 mEq/L
137
nominal setting
130 mEq/L
130
lowest setting
155 mEq/L
155
highest setting
2008K Hemodialysis Machine Operator's Manual Rev P
NaturaLyte 2251-0 with 4 mEq/L Acetate
Bicarbonate Potassium
33 2.0
33 1.9
33 2.3
Bicarbonate Potassium
33 2.0
33 1.9
33 2.3
Chapter 3—Setting Treatment Parameters
Calcium Magnesium
2.5 1.0
2.3 0.9
2.9 1.2
Calcium Magnesium
2.5 1.0
2.3 0.9
2.9 1.2
Acetate Dextrose
4.0 100
3.7 93
4.7 117
Acetate Dextrose
8.0 100
7.5 93
9.4 117
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