Removing Buffered Mobile Phase - Waters ACQUITY Refractive Index Detector Overview And Maintenance Manual

If you are not running the detector for less than 24 hours, set the flow rate to
0.1 mL/min, and keep the solvent manager operating to minimize the amount
of time the detector needs for reequilibration when you use it again.
To shut down the detector for more than 24 hours:
1. Flush all flow paths with 100% organic solution.
2. Stop the solvent flow to the solvent manager.
3. Power-off the detector.

Removing buffered mobile phase

To remove mobile phase from the fluid path of the detector:
1. Replace the buffered mobile phase with 100% HPLC-quality water and
flush the system for 10 minutes at 2 mL/min.
Important:
remove the column before flushing.
2. Replace the 100% water mobile phase with a 100% organic solution, and
flush the system for 10 minutes at 2 mL/min.
Follow the recommended procedures for injector purging and priming for the
pump used with the ACQUITY system.
Power-off any peripheral devices before shutting down the detector. To
power-off the detector, press the power switch on the top, left side of the
detector door.
If the storage solvent is incompatible with the column,
Shutting down the detector
October 13, 2014, 715003547 Rev. C 67