Waters ACQUITY UPLC Operator's, Overview And Maintenance Manual page 141

Stop any currently running mobile phase before replacing the
Requirement:
frit in the in-line filter unit.
Required materials
• Gloves: clean, powder-free, chemical-resistant
• Replacement frit
Required tools
5/16-inch open-end wrench (2)
To replace the frit in the in-line filter unit:
1. After allowing sufficient time for cooling, open the column heater,
column manager, or auxiliary column manager door.
2. Remove the column components (column, in-line filter unit, and active
preheater or stabilizer tubing assembly).
Column components:
Column
3. Detach the active preheater or column stabilizer tubing assembly from
the column in-line filter unit.
Requirement:
Flow
In-line filter unit
Do not detach the in-line filter unit from the column inlet.
Maintaining the column compartments
Active preheater or column
stabilizer tubing assembly
Inlet
Reusable fitting
TP02873
137