Waters ACQUITY UPLC Operator's, Overview And Maintenance Manual page 132

Warning:
and then allow the column compartment and its components to cool for
60 minutes before touching them. Monitor the column compartment's
internal temperature to ensure all components are cool.
Caution:
chemical-resistant, powder-free gloves when replacing the active
preheater assembly.
Caution:
• turn the column, not the fitting, when installing or removing the
column to prevent the active preheater tubing from turning with the
fitting.
• do not grasp and turn the assembly.
• do not suspend or hang the active preheater tubing.
Required materials
• Gloves: clean, powder-free, chemical-resistant
• Replacement active preheater assembly
Required tools
• 1/4-inch open-end wrench
• 5/16-inch open-end wrench
To remove the active preheater assembly:
1. Stop any running mobile phase before replacing the active preheater
assembly.
2. After allowing sufficient time for the instrument to cool, open the
column heater, column manager, or auxiliary column manager door.
3. Disconnect the inlet tubing:
• Column heater – disconnect the tubing from injector port 6 of the
sample manager.
• 30-cm column heater – disconnect the tubing from injector port 6 of
the sample manager.
128
To prevent burn injuries, set the column temperature to Off,
To prevent contaminating system components, wear clean,
To avoid damaging the active preheater assembly,