Potential Causes Of Leak Rate Test Failure - Agilent Technologies InfinityLab LC Series User Manual

7 Test Functions and Calibration
Leak Rate Test

Potential Causes of Leak Rate Test Failure

Secondary Leak
If a leak is found for movement of piston 2 (secondary leak), the following
reasons are possible:
Probable cause
1
2
3
4
5
6
Primary Leak
If a leak is found for movement of piston 1 (primary leak), any leak described for
piston movement 2 will cause a failure for piston 1 as well, as the liquid can move
through the outlet valve to chamber 2. Such cases need to be identified as
described before. Additionally, following causes are possible:
Probable cause
1
2
Agilent InfinityLab LC Series 1260 Infinity II Isocratic and Quaternary Pumps User Manual
System not flushed properly
Degassing efficiency is low
Purge valve not closed or defect
Blank nut not installed tightly
Outlet valve leaking (read below)
Leak at piston 2 or seal in chamber 2
Leak at piston 1 or seal in chamber 1
Leak at inlet valve
Suggested actions
Flush system for several minutes
Check degasser performance
Check purge valve
Tighten or replace blank nut
Replace outlet valve
Inspect piston, replace piston and/or seal
Suggested actions
Inspect piston, replace piston and/or seal
Replace inlet valve or inlet valve cartridge (AIV
only)
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