Replacing The Vent-Valve Cartridge - Waters ACQUITY UPLC Overview And Maintenance Manual

9. Reattach the compression fittings to the 250-µL mixer/filter, and then tighten them with
your fingers to the extent possible.
10. Using the 1/4-inch open-end wrench, tighten the fittings an additional 1/6-turn, for existing
fittings, or 3/4-turn, for new fittings.

3.14 Replacing the vent-valve cartridge

Warning:
working with hazardous materials. Consult the Material Safety Data Sheets regarding
the solvents you use. Additionally, consult the safety representative for your
organization regarding its protocols for handling such materials.
Notice:
powder-free gloves when performing this procedure.
Requirement:
this procedure.
Required tools and materials
• Chemical-resistant, powder-free gloves
• 1/4-inch open-end wrench
• 2-mm hex wrench
• Vent-valve cartridge
To replace the vent-valve cartridge:
1. In the console, select the solvent manager, and then click Interactive Display > Control
.
2. Ensure that the vent valve is set to the vent position.
Tip:
To change the setting to the vent position, click the underlined vent-valve position,
and select Vent.
3. Open the solvent manager's door.
4. Use the 1/4-inch open-end wrench to remove the fittings attached to the vent-valve
cartridge.
5. Use the 2-mm hex wrench to remove the hex screw at the 10 o'clock position on the vent-
valve cartridge.
Observe Good Laboratory Practice (GLP) at all times, particularly when
To avoid contaminating system components, wear clean, chemical-resistant,
Wear clean, chemical-resistant, powder-free gloves when performing
August 8, 2016, 715005050 Rev. C
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