Replacing The 100-Μl Mixer/Filter - Waters ACQUITY UPLC Overview And Maintenance Manual

Quaternary solvent manager
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5.
Place the new filters on the inlet manifold tubes.
6.
Connect the inlet manifold tubes (4) to the GPV outlets and tighten the fittings with your
fingers.
7.
Power-on the solvent manager.
8.
Prime the solvent manager (see
3.12 Replacing the 100-µL mixer/filter
Warning:
working with hazardous materials. Consult the Material Safety Data Sheets regarding
the solvents you use. Additionally, consult the safety representative for your
organization regarding its protocols for handling such materials.
Notice:
powder-free gloves when performing this procedure.
Requirement:
this procedure.
Required tools and materials
• Chemical-resistant, powder-free gloves
• 1/4-inch open-end wrench
• 5/8-inch open-end wrench
• 100-µL mixer/filter
To replace the 100-µL mixer/filter:
1.
Flush the solvent manager with nonhazardous solvent.
2.
Stop the solvent flow.
3.
Open the solvent manager's door.
4.
Using the 5/8-inch open-end wrench to hold the 100-µL mixer/filter in place, disconnect the
outlet compression fitting using the 1/4-inch open-end wrench.
Figure 3–16: Location of outlet compression fitting
Priming the solvent
Observe Good Laboratory Practice (GLP) at all times, particularly when
To avoid contaminating system components, wear clean, chemical-resistant,
Wear clean, chemical-resistant, powder-free gloves when performing
1
2
August 8, 2016, 715005050 Rev. C
manager).
Page 56

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