Intended Use Of The Qsm; Calibrating; Quality Control; Ism Classification: Ism Group 1 Class B - Waters ACQUITY UPLC Overview And Maintenance Manual

Intended use of the QSM

Waters designed the QSM for use in liquid chromatography applications. The QSM is not
intended for use in diagnostic applications.

Calibrating

To calibrate LC systems, adopt acceptable calibration methods using at least five standards to
generate a standard curve. The concentration range for standards must include the entire range
of QC samples, typical specimens, and atypical specimens.
When calibrating mass spectrometers, consult the calibration section of the operator's guide for
the instrument you are calibrating. In cases where an overview and maintenance guide, not an
operator's guide, accompanies the instrument, consult the instrument's online Help system for
calibration instructions.

Quality control

Routinely run three QC samples that represent subnormal, normal, and above-normal levels of a
compound. If sample trays are the same or very similar, vary the location of the QC samples in
the trays. Ensure that QC sample results fall within an acceptable range, and evaluate precision
from day to day and run to run. Data collected when QC samples are out of range might not be
valid. Do not report these data until you are certain that the instrument performs satisfactorily.
EMC considerations
Canada spectrum management emissions notice
This class A digital product apparatus complies with Canadian ICES-001.
Cet appareil numérique de la classe A est conforme à la norme NMB-001.

ISM classification: ISM group 1 class B

This classification has been assigned in accordance with IEC CISPR 11 Industrial Scientific and
Medical (ISM) instrument requirements.
Group 1 products apply to intentionally generated and/or used conductively coupled radio-
frequency energy that is necessary for the internal functioning of the equipment.
Class B products are suitable for use in both commercial and residential locations and can be
directly connected to a low voltage, power-supply network.
August 8, 2016, 715005050 Rev. C
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