Refractive Indices Of Common Solvents - Waters Alliance e2695 Operator's Manual

Refractive indices of common solvents

The following table lists the refractive indices for some common
chromatographic solvents. Use this table to verify that the solvent you intend
to use for your analysis has a refractive index (RI) significantly different from
the RIs of the sample components.
Refractive indices for common chromatographic solvents:
Solvent
Fluoroalkanes
Hexafluoroisopropanol
(HFIP)
Methanol
Water
Acetonitrile
Ethyl ether
n-Pentane
Acetone
Ethanol
Methyl acetate
Isopropyl ether
Ethyl acetate
1-Pentene
Acetic acid
Isopropyl chloride
Isopropanol
n-Propanol
Methylethylketone
Diethyl amine
n-Propyl chloride
Methylisobutylketone
RI Solvent
1.25 Tetrahydrofuran (THF)
1.2752 Amyl alcohol
1.329 Diisobutylene
1.33 n-Decane
1.344 Amyl chloride
1.353 Dioxane
1.358 Ethyl bromide
1.359 Methylene chloride
1.361 Cyclohexane
1.362 Ethylene glycol
1.368 N,N-Dimethyl Formamide
(DMF)
1.370 N,N-Dimethyl Acetamide
(DMAC)
1.371 Ethyl sulfide
1.372 Chloroform
1.378 Ethylene dichloride
1.38 Carbon tetrachloride
1.38 Dimethyl sulfoxide
(DMSO)
1.381 Toluene
1.387 Xylene
1.389 Benzene
1.394 Pyridine
July 29, 2013, 715003794 Rev. B
Wavelength selection
RI
1.408
1.410
1.411
1.412
1.413
1.422
1.424
1.424
1.427
1.427
1.428
1.438
1.442
1.443
1.445
1.466
1.477
1.496
~1.50
1.501
1.510
305