Thermo Scientific Vanquish VF-D20 Operating Manual page 93

Before Starting Sample Analysis
Vanquish Charged Aerosol Detectors Operating Manual
Before starting an analysis:
•
Make sure that the pump flow rate that is delivered to the charged
aerosol detector is within the specified range. See
page 164.
•
To deliver pump flow to the charged aerosol detector, follow these
steps:
a) Turn on the detector gas flow. See
pump flow must be turned off. Wait at least 5 minutes before
you continue.
b) Turn on the pump flow to the detector. Have the pump deliver
flow to the detector.
•
Check the liquid level in the solvent reservoirs. Verify that the
amount of solvent is sufficient for the analysis.
•
Verify that the doors of the modules in the Vanquish system are
closed.
• Make sure that the chromatography system is properly equilibrated.
System equilibration should include the following operations:
♦
Purging the pump (all channels)
♦
Flushing the entire chromatography system with the starting
solvent to rinse out any solvent from a previous analysis run
♦
Warming up (or cooling down) all temperature-controlled
devices in the system to the starting temperature
Temperature-controlled devices can be, for example,
♦
Column compartment and post-column cooler
♦
Thermostatting in the autosampler
♦
Flow cell in a fluorescence detector
♦
Evaporation tube in a charged aerosol detector
♦
Turning on the lamp (or lamps) in the UV/VIS detector
♦
Monitoring the pump pressure and pressure ripple and checking
that the pressure is stable and the ripple within reasonable
limits for the application
6 • Operation
section 9.1,
section 6.5.3, page 99. The
Page 93