Thermo Scientific Vanquish VF-D20 Operating Manual page 78

5 • Installation
Connecting the Capillary Between Flow Cell and Nebulizer
5.6.5.2
Preparations
Follow these steps
Page 78
If the charged aerosol detector is the second detector in the Vanquish
system flow path, for example after the diode array detector, connect
the capillary between flow cell and nebulizer.
Observe the following guidelines for series flow configuration:
•
The charged aerosol detector must be the last detector connected in
the flow path.
•
Other detectors contribute to extra-column volume, which may have
an adverse effect on the peak shape measured by the charged
aerosol detector.
• If the charged aerosol detector is the second detector in the
Vanquish system after the diode array detector
Be aware of the backpressure limit of the LightPipe™ flow cell in the
diode array detector. Connect the capillary from the flow cell
directly to the nebulizer. Avoid connecting any additional
components in the flow path between the two detectors. Refer to
the Operating Manual for the diode array detector.
•
If you want to bypass the flow cell, use the Viper union to
interconnect the capillary from the column with the capillary
connected to the nebulizer. Keep the capillary connection as short as
possible to minimize peak dispersion.
•
See section 5.6.5, page
•
Observe all notes and specifications for the flow cell in the first
detector in the Vanquish system. Refer to the Operating Manual for
this detector.
1. Connect the capillary from the column to the flow cell inlet. Refer to
the instructions in the Operating Manual for the first detector in the
Vanquish system flow path.
2. Route the connecting capillary from the flow cell outlet upward to
charged aerosol detector.
Vanquish Charged Aerosol Detectors Operating Manual
76.