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7.3.2
Regional anticoagulation with citrate
7.3.2.1
General information on citrate anticoagulation
Regional anticoagulation
with citrate
CVVHD with citrate anticoagulation
Blood flow
Ultrafiltration
UF goal
Cont. heparin adm.
Dialysate
Citrate / blood (citrate dose)
Calcium / filtrate (calcium dose)
Temperature
postCVVHDF with citrate anticoagulation
Blood flow
Ultrafiltration
UF goal
Cont. heparin adm.
Dialysate
Substituate
Citrate / blood (citrate dose)
Calcium / filtrate (calcium dose)
Temperature
Fresenius Medical Care multiFiltrate IFU-EN-UK 15A-2015
Citrate can be used for regional anticoagulation and is directly
eliminated from the blood to a large extent by the filter during the CRRT
treatment. The part of the citrate which is inevitably infused into the
body is quickly metabolised by most patients. In the majority of patients,
this prevents a clinically relevant increase of the systemic citrate
concentration.
Min.
10
Off / 10
Off / 10
Off / 0.1
600
2.0
0
Off / 35
Min.
10
Off / 10
Off / 10
Off / 0.1
600
600
2.0
0.1
Off / 35
Chapter 7: Functional description
Max.
Resolution
200
10
1800
10
10,000
10
25
0.1
4800
50
6.0
0.1
3.0
0.1
39
0.5
Max.
Resolution
200
10
1200
10
14,400
50
25
0.1
4800
50
2400
50
6.0
0.1
3.0
0.1
39
0.5
Unit
ml/min
ml/h
ml
ml/h
ml/h
mmol/l
mmol/l
°C
Unit
ml/min
ml/h
ml
ml/h
ml/h
ml/h
mmol/l
mmol/l
°C
7-17
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