Waters Prep Series Installation And Maintenance Manual page 103

Chromatography troubleshooting (Continued)
Symptom
Baseline drift, slow
Baseline noise,
short-term (30 sec to 1
min) cycling
Possible cause
Solvent contaminated
Decreased UV lamp
energy
Ambient temperature
fluctuations
UV detector flow cell
leaking (internal,
cross-port)
Dirty flow cell
Inadequate solvent
blending in pump
Flow fluctuating
Solvent not mixed
(short or long term
cycling)
AC power source (short
or long term cycling)
Radio frequency noise
(short or long term
cycling)
Corrective action
Use fresh solvents.
Check lamp energy
(detector
documentation).
Stabilize operating
environment
temperature enough to
allow full equilibration.
Check flow cell; tighten
connections.
Clean flow cell
(detector
documentation).
Connect high flow
mixer.
Stabilize flow.
Stir solvent.
Disconnect other
instruments on the
power line; try a
different wall outlet;
have line voltage
checked; use power
conditioner.
Eliminate interference.
Troubleshooting 3-19