Waters Prep Series Installation And Maintenance Manual page 105

Chromatography troubleshooting (Continued)
Symptom
Baseline noise, random
Possible cause
Air in detector
Solvents not properly
degassed
Flow erratic, pump not
primed
Solvents contaminated
Column contaminated
Dirty flow cell
Analog output cable not
properly connected
between the Prep
system and data
system, recorder, or
integrator
System grounded
improperly
Recorder voltage
incorrect
Unit not cooling
properly
Radio frequency noise
Defective detector
Corrective action
Purge UV detector to
remove air.
Sparge solvents.
Prime the pump; check
for air in the pump,
failing seals.
Use fresh solvent.
Clean or replace
column.
Clean flow cell (see
detector
documentation).
Properly connect cable.
Plug all system
components into a
single power strip.
Set recorder to proper
voltage.
Operate unit with
covers installed.
Eliminate interference.
Troubleshoot detector.
Troubleshooting 3-21