Peak resolution troubleshooting
Resolution
problem
Are peaks
eluting at correct
retention time?
Yes
Are peaks
broadening?
(column)
No
Are peaks
broadening?
(not column)
No
No
Continued on next page
Call Waters
technical service
3-14
Troubleshooting, Testing, and Maintenance
Troubleshoot
No
retention time
problem
Check column by
Yes
determining plate
count. low?
Inline filter or
Yes
guard column
clogged?
No
Injector/column
tubing diameter
too large?
No
Detector/column
tubing diameter
too large?
No
No
Problem with
injector?
Replace column
Yes
and check plate
count. low?
Yes
Clean/replace filter
or guard column
Yes
Use correct
diameter tubing
Yes
Use correct
diameter tubing
Yes
Troubleshoot
injector
Yes