Waters Prep Series Installation And Maintenance Manual page 88

General PrepLC troubleshooting (Continued)
Symptom
Pump cavitating
RI detector leaking
internally or from
purge port
Peak retention times
halved
Unable to enter a
flow rate above
150 mL/min
Pulsing flow from
waste line
3-4 Troubleshooting, Testing, and Maintenance
Possible cause
Solvent reservoirs
positioned below solvent
proportioning valve
Leak in tubing
connections or loose
fittings prior to inlet
check valve, causing
aspiration of air (fluid
leak may not be visible)
Solvent inlet filter
restricting flow
Cell damaged –
maximum flow rate or
pressure of RI cell
exceeded
Incorrect pump head
volume entered on
PUMP
CONFIGURATION
screen
Incorrect pump head
volume entered on
PUMP
CONFIGURATION
screen
Dirty check valve(s)
Corrective action
Place solvents on bench
beside fluid handling
unit.
Eliminate leak, tighten
fittings, replace ferrules.
Clean or replace filters.
Do not exceed 5 mL/min
(2414, 2410, and 410
Detectors). Do not exceed
100 psi for any Waters RI
detector.
Replace detector flow cell
if necessary (see detector
operator's guide).
For PrepLC operation
with 1000-µL pump
heads, enter 1000 for
pump head volume on
the PUMP
CONFIGURATION
screen.
For operation with
1000-µL pump heads,
enter 1000 for pump
head volume on the
PUMP
CONFIGURATION
screen.
Clean check valve(s).