Hologic ThinPrep Operator's Manual page 12

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Table 7: 6x6 "True AGUS" Contingency Table For All Sites Combined
All 10 Cases Determined To Be AGUS By Adjudication
NEG
ASCUS
AGUS
LSIL
HSIL
CA
TOTAL
Among the 10 cases determined by the adjudication panel to be AGUS, 4 (40.0%) cases in the
Imager Review arm and 3 (30.0%) cases in the Manual Review arm were diagnosed as AGUS and
4 (40.0%) cases in the Imager Review arm and 2 (20.0%) cases in the Manual Review arm were
diagnosed as Negative.
Table 8: 6x6 "True LSIL" Contingency Table For All Sites Combined
All 236 Cases Determined To Be LSIL By Adjudication
NEG
ASCUS
AGUS
LSIL
HSIL
CA
TOTAL
Among the 236 cases determined by the adjudication panel to be LSIL, 155 (65.6%) cases in the
Imager Review arm and 152 (64.4%) cases in the Manual Review arm were diagnosed as LSIL and
17 (7.2%) cases in the Imager Review arm and 21 (8.9%) cases in the Manual Review arm were
diagnosed as Negative.
Table 9: 6x6 "True HSIL" Contingency Table For All Sites Combined
All 138 Cases Determined To Be HSIL By Adjudication
NEG
ASCUS
AGUS
LSIL
HSIL
CA
TOTAL
Unadjudicated Manual Review Arm Diagnosis
NEG
ASCUS
AGUS
-
2
1
-
-
1
2
-
1
-
-
-
-
-
-
-
-
-
2
2
3
Unadjudicated Manual Review Arm Diagnosis
NEG
ASCUS
AGUS
-
4
-
13
16
-
-
-
-
8
20
-
-
-
-
-
-
-
21
40
0
Unadjudicated Manual Review Arm Diagnosis
NEG
ASCUS
AGUS
-
1
-
2
4
-
-
-
-
1
-
-
3
3
1
-
-
-
6
8
1
LSIL
HSIL
CA
TOTAL
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
0
1
2
LSIL
HSIL
CA
TOTAL
12
1
-
20
1
-
-
-
-
115
12
-
5
9
-
-
-
-
152
23
0
LSIL
HSIL
CA
TOTAL
-
1
-
2
1
-
-
-
-
10
6
-
9
91
1
-
1
1
21
100
2
MAN-03938-001 Rev. 002 page 8 of 23
4
1
4
0
0
1
10
17
50
0
155
14
0
236
2
9
0
17
108
2
138

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