Agilent Technologies 1260 Infinity II User Manual page 47

3
Using the Module
Solvent Information
Material Information
Materials in the flow path are carefully selected based on Agilent's
experiences in developing highest quality instruments for HPLC analysis over
several decades. These materials exhibit excellent robustness under typical
HPLC conditions. For any special condition, please consult the material
information section or contact Agilent.
Disclaimer
Subsequent data was collected from external resources and is meant as a
reference. Agilent cannot guarantee the correctness and completeness of such
information. Data is based on compatibility libraries, which are not specific
for estimating the long-term life time under specific but highly variable
conditions of UHPLC systems, solvents, solvent mixtures and samples.
Information can also not be generalized due to catalytic effects of impurities
like metal ions, complexing agents, oxygen etc. Apart from pure chemical
corrosion, other effects like electro corrosion, electrostatic charging
(especially for non-conductive organic solvents), swelling of polymer parts etc.
need to be considered. Most data available refers to room temperature
(typically 20 – 25 °C, 68 – 77 °F). If corrosion is possible, it usually accelerates
at higher temperatures. If in doubt, please consult technical literature on
chemical compatibility of materials.
PEEK
PEEK (Polyether-Ether Ketones) combines excellent properties regarding
biocompatibility, chemical resistance, mechanical and thermal stability. PEEK
is therefore the material of choice for UHPLC and biochemical
instrumentation.
It is stable in the specified pH range (for the Bio-inert LC system: pH 1 – 13,
see bio-inert module manuals for details), and inert to many common solvents.
There is still a number of known incompatibilities with chemicals such as
chloroform, methylene chloride, THF, DMSO, strong acids (nitric acid > 10 %,
sulphuric acid > 10 %, sulfonic acids, trichloroacetic acid), halogenes or aequous
halogene solutions, phenol and derivatives (cresols, salicylic acid etc.).
When used above room temperature, PEEK is sensitive to bases and various
organic solvents, which can cause it to swell. Under such conditions normal
PEEK capillaries are very sensitive to high pressure. Therefore Agilent uses
1260 Infinity II Flexible Pump User Manual 47