Waters Xevo TQ-S micro IVD Manuals

Manuals and User Guides for Waters Xevo TQ-S micro IVD. We have 1 Waters Xevo TQ-S micro IVD manual available for free PDF download: Overview And Maintenance Manual

Waters Xevo TQ-S micro IVD Overview And Maintenance Manual (146 pages)

Brand: Waters | Category: Laboratory Equipment | Size: 3 MB

General Information
3
Copyright Notice
3
Trademarks
3
Contacting Waters
4
Xevo TQ-S Micro IVD Manufacturing Information
4
Safety Considerations
4
Safety Hazard Symbol Notice
4
Considerations Specific to the Xevo TQ-S Micro IVD
5
Power Cord Replacement Hazard
5
High Temperature Hazard
6
High Voltage Hazard
6
Bottle Placement Prohibition
7
Electrical Power Safety Notice
7
Equipment Misuse Notice
8
Safety Advisories
8
Operating this Instrument
8
Applicable Symbols
8
Audience and Purpose
9
Intended Use of the Xevo TQ-S Micro IVD
9
Compliance with Medical Device Regulations
9
Calibrating
10
Quality Control
10
EMC Considerations
11
ISM Classification: ISM Group 1 Class a
11
Canada Spectrum Management Emissions Notice
11
Australian Sponsor Information
12
Table of Contents
13
Specifications and Operating Modes
19
Uses and Compatibility
19
Intellistart Technology
20
ACQUITY UPLC I-Class / Xevo TQ-S Micro IVD System
21
Software and Data System
21
Ionization Source
22
Intellistart Fluidics System
22
Functionality
22
System Operation
23
Ion Optics
24
MS Operating Modes
24
MS/MS Operating Modes
25
Product (Daughter) Ion Mode
25
Precursor (Parent) Ion Mode
26
Typical Application
26
Multiple Reaction Monitoring Mode
26
Constant Neutral Loss Mode
27
Sample Inlet
28
Leak Sensors
28
Vacuum System
29
Preparing for Operation
31
Starting the Mass Spectrometer
31
Verifying the Instrument's State of Readiness
32
Monitoring the Instrument Leds
32
Power Led
32
Operate LED
32
Tuning and Calibration Information
33
Running the Instrument at Different Flow Rates
33
Preparing the Intellistart Fluidics System
33
Installing the Reservoir Bottles
33
Purging the Infusion Pump
34
Rebooting the Instrument
35
Leaving the Mass Spectrometer Ready for Operation
35
Emergency Shutdown of the Mass Spectrometer
36
Installing and Removing the ESI Probe
37
Installing the ESI Probe
37
Removing the ESI Probe
39
Maintenance Procedures
41
Maintenance Schedule
41
Spare Parts
43
Troubleshooting with Connections INSIGHT
43
Safety and Handling
44
Preparing the Instrument for Operations on or Inside Its Source
44
Removing and Refitting the Source Enclosure
45
Removing the Source Enclosure from the Instrument
45
Fitting the Source Enclosure to the Instrument
46
Operating the Source Isolation Valve
47
Removing O-Rings and Seals
49
Cleaning the Instrument Case
50
Emptying the Exhaust Trap Bottle
50
Gas Ballasting the Oil-Filled Roughing Pump
52
Inspecting the Roughing Pump Oil Level
53
Adding Oil to the Roughing Pump
54
Required Materials
54
Replacing the Roughing Pump Oil
55
Replacing the Roughing Pump's Oil Demister Element
57
Cleaning the Source Components
61
Cleaning the Sampling Cone Assembly
61
Removing the Sampling Cone Assembly from the Source
62
Disassembling the Sampling Cone Assembly
63
Cleaning the Sample Cone and Cone Gas Nozzle
65
Assembling the Sampling Cone Assembly
66
Fitting the Sampling Cone Assembly to the Source
67
Cleaning the Ion Block Assembly
68
Removing the Ion Block Assembly from the Source Assembly
68
Disassembling the Source Ion Block Assembly
70
Required Materials
70
Cleaning the Ion Block Components
74
Assembling the Source Ion Block Assembly
75
Fitting the Ion Block Assembly to the Source Assembly
76
Cleaning the Ion Guide Assembly
77
Removing the Pumping Block Assembly and Ion Guide Assembly from the Instrument
77
Removing the Ion Guide Assembly and Differential Aperture from the Pumping Block Assembly
78
Removing the Differential Aperture Support and the Differential Aperture from the Ion Guide Assembly
79
Cleaning the Differential Aperture
81
Cleaning the Ion Guide Assembly
81
Fitting the Differential Aperture and the Differential Aperture Support Onto the Ion Guide Assembly
84
Fitting the Ion Guide Assembly and Differential Aperture Onto the Pumping Block Assembly
84
Fitting the Pumping Block Assembly and Ion Guide Assembly Onto the Instrument
85
Maintaining the ESI Probe
86
Replacing the Probe Tip and Gasket
86
Replacing the ESI Probe Capillary
88
Replacing the Ion Block Source Heater
101
Replacing the Source Assembly Seals
105
Removing the Probe Adjuster Assembly Probe and Source Enclosure Seals
105
Fitting the New Source Enclosure and Probe Adjuster Assembly Seals
107
Replacing the Air Filter
108
Required Material
108
Replacing the Instrument's Fuses
109
A January 30, 2020Safety Advisories
111
Warning Symbols
111
Specific Warnings
112
Biohazard Warning
113
Notices
114
Bottles Prohibited Symbol
114
Required Protection
115
Warnings that Apply to All Waters Instruments and Devices
115
Warnings that Address the Replacing of Fuses
118
Electrical and Handling Symbols
120
Electrical Symbols
120
Handling Symbols
120
B External Connections
123
External Wiring and Vacuum Connections
123
Connecting the Oil-Filled Roughing Pump
124
Required Materials
124
Connecting Electric Cables to the Oil-Filled Roughing Pump
127
Connecting the Edwards Oil-Free Roughing Pump
128
Connecting Electric Cables to the Edwards -Free Roughing Pump
130
Connecting to the Nitrogen Gas Supply
131
Connecting to the Collision Cell Gas Supply
132
Connecting the Nitrogen Exhaust Line
133
Connecting the Liquid Waste Line
135
Connecting the Workstation
136
I/O Signal Connectors
137
Signal Connections
138
Connecting to the Power Supply
140
C January 30, 2020Materials of Construction and Compliant Solvents
141
Preventing Contamination
141
Items Exposed to Solvent
141
Solvents Used to Prepare Mobile Phases
142
D Plumbing the Intellistart Fluidics System
143
Preventing Contamination
143
The Selector Valve
143
Plumbing Schematic
144
Tubing and Connection Specifications
144

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Waters Xevo TQ-S micro IVD Overview And Maintenance Manual (146 pages)

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