Optimizing The Performance; Optimization Guidelines - Thermo Scientific Corona Veo Operating Manual

6 • Operation
6.7

Optimizing the Performance

6.7.1

Optimization Guidelines

General Guidelines
Page 140
This section provides information for best performance of the detector
and gives hints on what you can do to optimize the performance further.
For information on the default parameters on the detector display, see
section 6.4, page 107.
Consider the following guidelines for optimization of the detector
performance:
•
Consider the influences of the parameters on the detection (see
section 6.7.2 Overview of Optimization Parameters, page
•
Ensure that the operating conditions are suitable. This includes:
♦ Stable environmental conditions, such as a stable temperature
♦
No air drafts
♦
No vibrations or mechanical shocks caused by external sources
♦
Stable backpressure and correct waste and leak drainage setup
•
Use an on-line degasser to degas the solvent in the pump.
•
Monitor the usage of specific detector components that are subject
to wear and stress and schedule appropriate maintenance intervals.
See section 7.4.1 Maintenance Plan, page
•
Observe the guidelines and recommendations on the use of mobile
phases with the charged aerosol detector. See
Phase Guidelines for the Detector, page
•
Maintain the nitrogen or air source for your detector at regular
intervals to ensure optimum performance. Observe the instructions
in the User Documentation for the nitrogen generator.
•
When the mobile phase was stored over a period of time, high
background current may be observed. Replace old mobile phase
with freshly prepared mobile phase.
Charged Aerosol Detectors Corona Veo (RS) Operating Manual
141).
170.
section 6.5.1 Mobile
123.