3
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Detector Overview
3.1
Detector Features
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The detector comprises the following main features:
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Charged aerosol detection (CAD) method for liquid chromatography
for detection of all non-volatile and many semi-volatile analytes
•
Detection based on measuring charge that is proportional to the
amount of analyte, and, for non-volatile analytes, independent of
the chemical structure of the analyte
In comparison to UV detection, a chromophore is not required for
detection, and in comparison to mass spectrometry, ionization of
the analyte is not necessary.
•
Detection with great sub-nanogram sensitivity and a wide dynamic
range
•
FocusJet™ nebulizer with concentric design for extended low pump
flow rate range
•
Adjustable evaporation temperature for optimization of analyte
response and use with a wider range of eluents
♦
Corona Veo RS detector: Adjustable range for the evaporation
temperature
♦
Corona Veo detector: Selectable evaporation temperatures
•
Fast data sampling for full compatibility with HPLC and UHPLC
applications
•
Detector control by the Chromeleon Chromatography Management
System for high degree of system integration, as well as maximum
analysis efficiency due to comprehensive data analysis and
evaluation features in Chromeleon
Charged Aerosol Detectors Corona Veo (RS) Operating Manual