Mode To Mode; Xb Analysis; Xb Theory; Target Values - Beckman Coulter COULTER HmX Operator's Manual

Hematology analyzer
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STARTUP AND CONTROLS

MODE TO MODE

2.5
MODE TO MODE
Beckman Coulter recommends that you perform a mode to mode quality-control check at
intervals established by your laboratory. Run a normal whole blood sample multiple times in
both the Primary and Secondary modes and compare the mean results. For an N of 10, the
mean results should compare within the limits listed below. If you use an N of less than 10,
you will need to establish your own limits.
Secondary mode-to-Primary mode comparison limits for an N of 10 are:
WBC
RBC
Hgb
Plt
Investigate any failure to recover values within expected limits. If you cannot resolve the
problem, contact your Beckman Coulter Representative.
2.6
X
ANALYSIS
B
X
Theory
B
X
analysis is a quality control method that monitors instrument performance by tracking the
B
MCV, MCH and MCHC parameters of patient samples. The method uses the red blood cell indices
because they tend to remain fairly stable and show little variance between patient samples.

Target Values

Dr. Brian Bull (the creator of X
index:
MCV - 89.5
MCH - 30.5
MCHC - 34.0
These constants were established using a general hospital population. Each laboratory should
begin with these target values and then adjust them for their own patient population. X
target values are set up in the DMS. See Chapter 6, Set Up,
2-24
3
+ 0.4 X 10
cells/µL or <5%, whichever is greater
6
+ 0.20 X 10
cells/µL or <2%, whichever is greater
+ 0.3 g/dL or <2%, whichever is greater
3
+ 20 X 10
cells/µL or <7%, whichever is greater
analysis) has determined the following target values for each
B
.
XB LIMITS
B
PN 4237519CB

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