Agilent Technologies InfinityLab LC Series User Manual page 112

5
Preparing the Module
Solvent Information
Fused silica and Quartz (SiO
Fused silica is used in Max Light Cartridges. Quartz is used for classical flow cell
windows. It is inert against all common solvents and acids except hydrofluoric
acid and acidic solvents containing fluorides. It is corroded by strong bases and
should not be used above pH 12 at room temperature. The corrosion of flow cell
windows can negatively affect measurement results. For a pH greater than 12,
the use of flow cells with sapphire windows is recommended.
Gold
Gold is inert to all common HPLC solvents, acids and bases within the
specified pH range. It can be corroded by complexing cyanides and
concentrated acids like aqua regia.
Zirconium Oxide (ZrO
Zirconium Oxide is inert to almost all common acids, bases and solvents.
There are no documented incompatibilities for HPLC applications.
Platinum/Iridium
Platinum/Iridium is inert to almost all common acids, bases and solvents.
There are no documented incompatibilities for HPLC applications.
Fluorinated polymers (PTFE, PFA, FEP, FFKM, PVDF)
Fluorinated polymers like PTFE (polytetrafluorethylene), PFA
(perfluoroalkoxy) and FEP (fluorinated ethylene propylene) are inert to
almost all common acids, bases, and solvents. FFKM is perfluorinated rubber,
which is also resistant to most chemicals. As an elastomer, it may swell in
some organic solvents like halogenated hydrocarbons.
TFE/PDD copolymer tubings, which are used in all Agilent degassers except
1322A, are not compatible with fluorinated solvents like Freon, Fluorinert, or
Vertrel. They have limited life time in the presence of Hexafluoroisopropanol
(HFIP). To ensure the longest possible life with HFIP, it is best to dedicate a
particular chamber to this solvent, not to switch solvents, and not to let dry
out the chamber. For optimizing the life of the pressure sensor, do not leave
HFIP in the chamber when the unit is off.
The tubing of the leak sensor is made of PVDF (polyvinylidene fluoride), which
is incompatible to the solvent DMF (dimethyl formamide).
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Agilent InfinityLab LC Series Vialsamplers User Manual