Best Practices - AB Sciex 4500 Series System User's Manual

Cleaning and Maintenance
Note: Follow all applicable local regulations. For health and safety guidelines, refer to
Health and Safety Precautions
Note: For consumables ordering information and inquiries, call 877-740-2129 (U.S.
only), or visit www.absciex.com.
Required Tools and Materials
• Powder free gloves (nitrile recommended)
• Safety glasses
• Laboratory coat
• Fresh, high quality water (at least 18 Mohm de-ionized water [DI water] or ultra-pure
HPLC-grade water). Old water can contain contaminants which can further
contaminate the mass spectrometer.
• HPLC- or LCMS-grade methanol, isopropanol (2-propanol), or acetonitrile
• Cleaning solution. Use one of:
• 100% methanol
• 100% isopropanol
• 50:50 acetonitrile:water solution (freshly prepared)
• 50:50 acetonitrile:water with 0.1% acetic acid solution (freshly prepared)
Caution: Do not use chlorinated solvents.
Table D-2 Tools and Supplies Available from AB SCIEX
Description
Small polyester swab (thermally bonded)
Small lint-free wipe (11 cm x 21 cm); available in Consumables kits

Best Practices

WARNING! Radiation Hazard, Biohazard, or Toxic Chemical Hazard:
Determine whether instrument decontamination is required prior to
cleaning. Instrument decontamination should be conducted prior to
cleaning if radioactive materials, biological agents, or toxic chemicals
have been used with an instrument.
• Always wear clean, powder-free gloves for the cleaning procedures.
• After cleaning the instrument components and before reassembling them, put on a
clean pair of gloves.
• Do not use cleaning supplies other than those specified in this procedure.
• If possible, prepare cleaning solutions just before beginning.
4500 Series of Instruments
136 of 142
for more information.
P/N
1017396
WC018027
System User Guide
Document Number: D5030863 A