Best Practices - AB Sciex QTRAP 4500 LC/MS/MS system System User's Manual

Qtrap 4500 series
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Best Practices

WARNING! Toxic Chemical Hazard: Follow all safety guidelines and applicable
local regulations when handling, storing, and disposing of chemicals. For health
and safety guidelines, refer to
WARNING! Potential Radiation Hazard, Biohazard, or Toxic Chemical
Hazard: Determine whether decontamination is required prior to cleaning.
Decontamination should be conducted prior to cleaning if radioactive
materials, biological agents, or toxic chemicals have been used with the
system.
WARNING! Environmental Hazard: Do not dispose of system components,
cleaning materials, or chemicals in municipal waste. Follow established
procedures when disposing of components, cleaning materials, and chemicals.
Always wear clean, powder-free gloves for the cleaning procedures.
After cleaning the mass spectrometer components and before reassembling them,
put on a clean pair of gloves.
Do not use cleaning supplies other than those specified in this procedure.
Prepare cleaning solutions just before beginning the procedure, if possible.
Prepare and store all organic solutions and organic-containing solutions in very
clean glassware only. Never use plastic squirt bottles. Contaminants can leach from
these bottles and further contaminate the mass spectrometer.
Allow only the center area of the wipe to contact the instrument surface. Cut edges
can leave fibers behind.
Tip!
Figure 13-1 Example: Folding the Wipe
To avoid cross-contamination, allow the wipe or swab to contact the surface once,
and then discard it.
Larger parts of the vacuum interface, such as the curtain plate, may require several
cleanings, using multiple wipes.
To avoid contaminating the solution, pour the solution on the wipe or swab.
4500 Series of Instruments
122 of 138
Chemical Precautions on page
Wrap the wipe around a thermally-bonded polyester swab.
11.
System User Guide
RUO-IDV-05-0264-A

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