AB Sciex 4500 Series System User's Manual page 52

Basic Acquisition Methods
Figure 5-1 Ion optics path and parameters (Continued)
Item Parameter
7 Fixed LIT Fill
Time
7 DFT (Dynamic
Fill Time)
8 CEM (CEM)
4500 Series of Instruments
52 of 142
Parameter Use
Type
Compound The Fixed LIT Fill Time parameter
controls the amount of time that the
LIT fills with ions.
Use the preset value.
Compound DFT will dynamically calculate the
length of time that ions are
collected in the LIT based on the
incoming ion signal. When DFT is
turned on the signal is optimized to
either increase sensitivity or
minimize space-charging.
Either select or clear the feature
based on the experiment.
In the Tools > Settings > Method
Options dialog, the Dynamic Fill
Time settings are optimized for the
10000 Da/s scan speed. These
settings are also suitable for other
LIT scan speeds.
Detector The CEM parameter controls the
voltage applied to the detector. The
voltage controls the detector
response.
Scan Type
EMS, EPI,
MRM, and MS/
MS/MS
EMS, EPI, ER,
and
MS/MS/MS
All
System User Guide
Document Number: D5030863 A