Clean The Front Of The Orifice Plate; Put The Instrument Back Into Service - AB Sciex 4500 Series System User's Manual

Note: Persistent spotting or filming is an indicator of contaminated solvent.

Clean the Front of the Orifice Plate

Note: If the standard orifice plate has a removable interface heater, do not remove the
heater during cleaning.
1. When cleaning a NanoSpray orifice plate, remove the interface heater and clean it:
i. Wipe the heater with a lint-free wipe dampened with water.
ii. Wipe the heater with a lint-free wipe dampened with cleaning solution.
2. Moisten the lint-free wipe with water and then wipe the front of the orifice plate.
Caution: Potential Instrument Damage: Do not insert a wire or metal brush
into the orifice, to avoid damaging the aperture.
3. Repeat step 2
4. Wait until the orifice plate is dry.
5. Inspect the orifice plate for solvent stains or lint, removing any residue with a clean,
slightly damp lint-free wipe.
Note: Persistent spotting or filming is an indicator of contaminated solvent.

Put the Instrument Back into Service

1. Install the curtain plate on the front end of the instrument.
2. Remove the protection from the ion source drain.
3. Install the ion source on the mass spectrometer.
4. Tighten the ion source by turning the ion source release latches down into the
locking position. (Refer to the ion source Operator's Guide.)
5. Activate the hardware profile.
System User Guide
Document Number: D5030863 A
using the cleaning solution.
Cleaning and Maintenance
4500 Series of Instruments
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