Waters ACQUITY UPLC Operator's, Overview And Maintenance Manual page 67

8. Square the flow cell assembly in front of the opening, and then insert it
slowly so that the guides on the front part of the cell flange engage the
rails in the sample cell compartment.
9. After the flange and rails are engaged, continue inserting the flow cell
until the dowel pins on the instrument engage the corresponding holes
on the cell holder.
10. Continue to insert the flow cell until the three thumbscrews align with
their holes in the bulkhead.
11. Hand tighten the thumbscrews. Confirm the screws are secure using a
screw driver.
12. Connect the inlet tubing to the main column connection and flow cell
inlet, and connect the outlet tubing to the flow cell outlet.
13. Reconnect the flow cell ID connector (if present).
14. Close the detector door.
15. Before you power-on the detector, ensure the flow cell is filled with
degassed, transparent solvent (acetonitrile or water) and free of air
bubbles.
Dowel pin
Rail
Guide
Flow cell handle
Maintaining the detector 55