Waters ACQUITY UPLC Operator's, Overview And Maintenance Manual page 64

14. Continue pumping the phosphoric acid mixture for an additional 3
hours.
15. Repeat steps 1 through 8 using 100% water as the solvent.
16. Repeat steps 1 through 8 using 50:50 (v/v) methanol/water as the
solvent.
17. Replace the sample and solvent manager bottle filters.
Replacing the flow cell
Caution:
• To avoid contaminating the flow cell, wear clean, chemical-resistant,
powder-free gloves when handling, removing, or replacing it.
• To avoid damaging the flow cell, handle it with care. Do not
disassemble the flow cell.
Controlling Contamination in Ultra Performance LC/MS and
See also:
HPLC/MS Systems (part number 715001307), available on the Waters web
site (www.waters.com).
Required materials
• 1/4-inch, flat-blade screwdriver
• Clean, chemical-resistant, powder-free gloves
• Flow cell
To replace the flow cell
1. Power-off the detector.
2. Stop the solvent flow.
3. Open the detector door, gently pulling its right-hand edge toward you.
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To avoid damaging electrical parts, never disconnect an
Caution:
electrical assembly while power is applied to an instrument. To
completely interrupt power to an instrument, set the power switch
to Off, and then unplug the power cord from the AC outlet. After
power is removed, wait 10 seconds thereafter before you
disconnect an assembly.