Waters ACQUITY UPLC Operator's, Overview And Maintenance Manual page 36

6. Attach the short length of outlet tubing from the backpressure regulator
to the outlet of the flow cell.
Backpressure regulator
7. Route the long end of the outlet tubing from the backpressure regulator,
through the channel clips along the front right side of the system, and
into a suitable waste container.
If a mass spectrometer or other detector is connected downstream of
Tip:
the detector, you need not install a backpressure regulator. The length of
the tubing connecting to the mass spectrometer or other detector helps
to maintain the backpressure on the flow cell.
24
Direction of flow from detector outlet
To waste
TP03260