Preparation And Operation; Installation Recommendations For Fittings - Waters ACQUITY UPLC Overview And Maintenance Manual

2

Preparation and operation

Note:
The system is shipped with a 15-µL needle. If you are not using the default ACQUITY
UPLC system configuration, which uses this needle, see
configuration parameters.
Before you prepare the sample manager for operation, prepare the solvent manager.
Tip:
For instructions explaining how to prepare the solvent manager, see the ACQUITY UPLC
Quaternary Solvent Manager Overview and Maintenance Guide or ACQUITY UPLC Binary
Solvent Manager Operator's Overview and Maintenance Information.
Warning:
To avoid personal contamination from contact with biologically hazardous or toxic
materials, before running samples,
• examine the injection valve, sample syringe, and all fittings for leaks, tightening them as
necessary to stop leakage;
• ensure that the doors to both the sample compartment and fluidics compartment remain
closed.

2.1 Installation recommendations for fittings

Warning:
working with hazardous materials. Consult the Material Safety Data Sheets regarding
the solvents you use. Additionally, consult the safety representative for your
organization regarding its protocols for handling such materials.
Warning:
To avoid personal contamination with biologically hazardous or toxic compounds,
wear clean, chemical-resistant, powder-free gloves when performing this procedure.
Warning:
Recommendations:
Observe Good Laboratory Practice (GLP) at all times, particularly when
To avoid eye injury, use eye protection when performing this procedure.
June 11, 2019, 715005051 Rev. D
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Modifying needle and extension loop