Agilent Technologies Agilent 1260 Infinity System User's Manual page 107

Tantalum (Ta)
Tantalum is inert to most common HPLC solvents and almost all acids
except fluoric acid and acids with free sulfur trioxide. It can be corroded
by strong bases (e.g. hydroxide solutions > 10 %, diethylamine). It is not
recommended for the use with fluoric acid and fluorides.
Stainless Steel (SST)
Stainless steel is inert against many common solvents. It is stable in the
presence of acids and bases in a pH range of 1 to 12.5. It can be corroded
by acids below pH 2.3. It can also corrode in following solvents:
• Solutions of alkali halides, their respective acids (for example, lithium
• High concentrations of inorganic acids like nitric acid, sulfuric acid and
• Halogenated solvents or mixtures which form radicals and/or acids, for
• Chromatographic grade ethers, which can contain peroxides (for
• Solutions of organic acids (acetic acid, formic acid, and so on) in
• Solutions containing strong complexing agents (for example, EDTA,
• Mixtures of carbon tetrachloride with 2- propanol or THF.
1260 Infinity Binary LC - System User Guide
iodide, potassium chloride, and so on) and aqueous solutions of
halogens.
organic solvents especially at higher temperatures (replace, if your
chromatography method allows, by phosphoric acid or phosphate buffer
which are less corrosive against stainless steel).
example:
→ 2 COCl
2 CHCl + O
3 2
This reaction, in which stainless steel probably acts as a catalyst,
occurs quickly with dried chloroform if the drying process removes the
stabilizing alcohol.
example, THF, dioxane, di- isopropylether). Such ethers should be
filtered through dry aluminium oxide which adsorbs the peroxides.
organic solvents. For example, a 1 % solution of acetic acid in methanol
will attack steel.
ethylene diamine tetra- acetic acid).
+ 2 HCl
2
Appendix
Solvent Information
107
6