Prevent Blocking Of Solvent Filters; Checking The Solvent Filters - Agilent Technologies Infinity II SFC Binary 1260 User Manual

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Prevent Blocking of Solvent Filters

Contaminated solvents or algae growth in the solvent bottle will reduce the

lifetime of the solvent filter and will influence the performance of the module.

This is especially true for aqueous solvents or phosphate buffers (pH 4 to 7).

The following suggestions will prolong lifetime of the solvent filter and will

maintain the performance of the module.

• Use a sterile, if possible amber, solvent bottle to slow down algae growth.

• Filter solvents through filters or membranes that remove algae.

• Exchange solvents every two days or refilter.

• If the application permits add 0.0001 – 0.001 M sodium azide to the solvent.

• Place a layer of argon on top of your solvent.

• Avoid exposure of the solvent bottle to direct sunlight.

Never use the system without solvent filter installed.

N O T E

The solvent filters are located on the low-pressure side of the binary pump. A

blocked filter therefore does not necessarily affect the high pressure readings

of the pump. The pressure readings cannot be used to check whether the

filters are blocked or not. If the solvent cabinet is placed on top of the binary

pump, the filter condition can be checked in the following way:

Remove the solvent inlet tube from the inlet port of the solvent selection valve

or the adapter at the active inlet valve. If the filter is in good condition, the

solvent will freely drip out of the solvent tube (due to hydrostatic pressure). If

the solvent filter is partly blocked only very little solvent will drip out of the

solvent tube.

1260 SFC Binary Pump

Using the Pump

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