Agilent Technologies Infinity II SFC Binary 1260 User Manual page 49

Tantalum (Ta)
Tantalum is inert to most common HPLC solvents and almost all acids except
fluoric acid and acids with free sulfur trioxide. It can be corroded by strong
bases (e.g. hydroxide solutions > 10 %, diethylamine). It is not recommended
for the use with fluoric acid and fluorides.
Stainless Steel (ST)
Stainless steel is inert against many common solvents. It is stable in the
presence of acids and bases in a pH range of 1 to 12.5. It can be corroded by
acids below pH 2.3. It can also corrode in following solvents:
• Solutions of alkali halides, their respective acids (for example, lithium
• High concentrations of inorganic acids like nitric acid, sulfuric acid and
• Halogenated solvents or mixtures which form radicals and/or acids, for
• Chromatographic grade ethers, which can contain peroxides (for example,
• Solutions of organic acids (acetic acid, formic acid, and so on) in organic
• Solutions containing strong complexing agents (for example, EDTA,
• Mixtures of carbon tetrachloride with 2-propanol or THF.
Titanium (Ti)
Titanium is highly resistant to oxidizing acids (for example, nitric, perchloric
and hypochlorous acid) over a wide range of concentrations and temperatures.
1260 SFC Binary Pump
iodide, potassium chloride, and so on) and aqueous solutions of halogens.
organic solvents especially at higher temperatures (replace, if your
chromatography method allows, by phosphoric acid or phosphate buffer
which are less corrosive against stainless steel).
example:
→ 2 COCl
2 CHCl + O
3 2
This reaction, in which stainless steel probably acts as a catalyst, occurs
quickly with dried chloroform if the drying process removes the stabilizing
alcohol.
THF, dioxane, di-isopropylether). Such ethers should be filtered through
dry aluminium oxide which adsorbs the peroxides.
solvents. For example, a 1 % solution of acetic acid in methanol will attack
steel.
ethylene diamine tetra-acetic acid).
+ 2 HCl
2
Using the Pump
Solvent Information
3
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