Best Practices For Filters; The Solvent Inlet Filters - Agilent Technologies 1100 Series User Manual

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Best Practices for Filters

Contaminated solvents or algae growth in the solvent bottle will reduce the
lifetime of the solvent filter and will influence the performance of the nano
pump. This is especially true for aqueous solvents, especially phosphate
buffers (pH 4 to 7). The following suggestions will prolong lifetime of the
solvent filter and will maintain the performance of the nano pump.
• Use sterile, if possible amber, solvent bottles to slow down algae growth.
• Filter solvents through filters or membranes that remove algae.
• Exchange solvents every two days or refilter.
• If the application permits add 0.1 to 1 milli-Molar sodium acid to the
• Place a layer of argon on top of your solvent.
• Avoid exposure of the solvent bottles to direct sunlight.

The solvent inlet filters

R
When opening capillary or tube fittings solvents may leak out. Please observe
WA RN ING
appropriate safety procedures (for example, goggles, safety gloves and protective
clothing) as described in the material handling and safety data sheet supplied by the
solvent vendor, especially when toxic or hazardous solvents are used.
The solvent filters are located on the low-pressure side of the nano pump. A
blocked filter therefore does not affect the pressure readings of the nano
pump. The pressure readings cannot be used to check whether the filter is
blocked or not. If the solvent cabinet is placed on top of the nano pump, the
filter condition can be checked in the following way:
Remove the solvent inlet tube from the inlet port of the solvent selection valve
or the adapter at the active inlet valve. If the filter is in good condition the
solvent will freely drip out of the solvent tube (due to hydrostatic pressure). If
the solvent filter is partly blocked only very little solvent will drip out of the
solvent tube.
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solvent.
1100 Series Nano Pump User Manual