Long-Term Shutdown - Thermo Scientific Vanquish VH-P10 Operating Manual

6 • Operation

6.10.2 Long-Term Shutdown

Shutting Down the Pump
Page 110
• Make sure that the temperature of the column does not exceed
40 °C.
•
When resuming operation, let the flow equilibrate and verify that
the operating parameters for the other system modules are set as
required before proceeding.
To interrupt operation for a longer period, follow the instructions in this
section.
TIP Shutting down the pump affects the operation of the system. When
shutting down the pump, also observe the shutting down instructions
for the other Vanquish system modules and take appropriate action
(refer to the Operating Manuals for the modules).
1. Flush the system with an appropriate, pure solvent (minimum HPLC-
grade).
Observe the following:
♦ Pump remains in the laboratory after shutdown
♦ If no additive is used, flush the system, for example with
methanol. 100% acetonitrile should not be used.
♦
If an additive is used, flush the system with several volumes
(for example, 1.0 mL/min for 10 minutes with the standard
system) of methanol and water (50:50) to prevent salt
buildup in the fluidics. If the solvents in the pump are not
miscible with water, use an appropriate intermediate
solvent.
♦ Pump shall be transported or shipped after shutdown
♦
If no additive is used, flush the system with isopropanol.
♦
If an additive is used, flush the system first with several
volumes (for example, 1.0 mL/min for 10 minutes with the
standard system) of methanol and water (50:50) to prevent
salt buildup in the fluidics. If the solvents in the pump are
not miscible with water, use an appropriate intermediate
solvent. Afterward, flush the system with isopropanol.
Vanquish Pumps (VH-P10) Operating Manual