Figure 31. Esi Nozzle And O-Ring - Thermo Scientific LTQ Series Hardware Manual

Thermo Scientific
 To clean the ESI nozzle
IMPORTANT Always use LC/MS-grade methanol (see
1. Disconnect the ESI nozzle from the ESI manifold (see steps
ESI probe" on page 59).
2. Clean the bore of the ESI nozzle with methanol.
The choice of solvent depends on the solubility of the chemical deposits.
3. Rinse the nozzle with methanol.
4. Dry the component with nitrogen gas to make sure that all the solvent evaporates.
5. Inspect the ESI nozzle O-ring and replace it if necessary

Figure 31. ESI nozzle and O-ring

6. Reconnect the ESI nozzle to the ESI manifold (see
If the needle is damaged, replace it. If the sheath gas is leaking at the interface between the
needle seal and the needle, replace the needle seal.

To replace the needle, needle seal, or both
1. Disconnect the ESI nozzle from the ESI manifold (see steps
ESI probe" on page 59).
2. Pull the ESI needle out of the ESI manifold.
3. To dislodge the needle seal, gently tap the ESI manifold against a hard surface.
If necessary, use the needle or another appropriate tool to push the needle seal out of the
ESI manifold. Tapping the manifold against a hard surface can also help to dislodge the
resistor and battery contact.
4. If necessary, replace the needle seal, the 26-gauge spray needle, or both.
5. Reassemble the ESI probe (see steps
Table 7
3–5
(Figure
ESI nozzle O-ring
page 62).
3–5
1–6 in "To assemble the ESI probe"
LTQ Series Hardware Manual
5
Maintenance
Ion Source Probe Maintenance
on page 55).
in "To disassemble the
31).
in "To disassemble the
on page 62).
61