Solvent Handling - Agilent Technologies InfinityLab LC Series User Manual

3 Using the Module
Solvent Recommendation for Agilent 1290 Infinity and 1290 Infinity II and 1260
Infinity II Flexible Pumps
Table 6
Inlet valves
Outlet valves
Corrosion of valves
C AU T I O N
Normal phase balls/valves corrode quickly in aqueous solutions and acids (at
or below pH 7).
 Do not use normal phase valves in applications running with aqueous
solutions.

Solvent Handling

Handling of Normal Phase Solvents
Observe the following recommendations when using normal phase solvents:
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1260 Infinity II Flexible Pump User Manual
Recommended valves for normal phase applications
Binary or High-Speed Pumps
(G7120A)
1290 Infinity Inlet Valve Type N
(G4220-60122)
1290 Infinity Outlet Valve Type N
(G4220-60128)
Always use fresh, filtered solvents. Exchange solvents every second day.
Prevent reactions caused by heat, light and oxygen. Use brown, firmly closed
bottles.
Whenever possible, use stabilizers, e.g. butylated hydroxytoluene (BHT) for
ethyl ether.
Use isopropanol (IPA) to flush out the previous solvent when converting a
system from normal phase to reverse phase, or vice versa.
Store all unused channels in IPA.
Don't turn off the pump while it is filled with solvents with low boiling points.
Generate a small flow throughout the used channels when the pump is not in
use.
Quaternary or Flexible Pumps
(G7104A/C)
1290 Infinity Quat Inlet Valve Type N
(G4204-60122)
1290 Infinity Outlet Valve Type N
(G4220-60128)
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