Section B: The Thinprep ® Imaging System Process - Hologic ThinPrep Imager Duo Operator's Manual

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NTRODUCTION
SECTION
Slides that have been prepared for screening are loaded into cassettes which are
placed into the Imaging Station. The operator uses a PC keyboard, mouse and
monitor to interact with the instrument via a graphic, menu driven interface.
A slide ID reader scans the slide accession ID and then the Imaging Station
scans the entire ThinPrep cell spot. The system identifies objects of interest
found on the slide, based on integrated optical density. (Refer to Figure 1-3,
ThinPrep Imaging Process.) The coordinates of 22 of those objects are recorded
and the slide is returned to its cassette. Following processing of each cassette of
slides, the slide ID and associated data record are sent to the Server and to the
ThinPrep Hnet
The Server acts as the central data manager for the ThinPrep Imaging System.
As slides are imaged by the Imager Duo and reviewed at the Review Scope, the
Server stores, retrieves and transmits information based on the slide ID. For
installations with multiple controllers, the server also controls the communica-
tion between all devices on the network. Some facilities only perform slide
screening, and a Server is used at that location to import data from an imaging
site.
The Cytotechnologist (CT) reviews slides at the Review Scope (RS). The RS con-
sists of elements of a standard microscope, augmented with automated capabil-
ities for viewing and marking the microscope slides. The RS contains a camera
which reads the slide ID when a slide is loaded on the stage. When a valid slide
accession ID has been identified at the RS, the Server sends the object of interest
coordinates for that ID and the CT is presented with the 22 fields of view deter-
mined for that slide. It is required that the CT review each of these fields of view
before completing a slide review.
As each field of view is being reviewed, the CT has the option to electronically
mark the contents of the target zone for subsequent physical marking at com-
pletion of the slide review. The CT always has the option to control the position
of the stage/slide manually, which provides complete freedom to move any
portion of the cell spot into the field of view for examination.
Note:
Before completing the review, the CT may revisit any locations and electronically
mark or unmark target zones, as desired. At the conclusion of electronically
marking the slide, physical marks are applied at those locations with semi-per-
manent translucent marker.
1.4 Imager Duo Operator's Manual
THE THINPREP IMAGING SYSTEM PROCESS
B
laboratory network, if your system is configured with it.
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The CT must screen the entire field of each of the 22 fields of view pre-
sented.