Hologic ThinPrep Imager Duo Operator's Manual page 24

Agreement among Laboratory Cytotechnologists/Pathologists
The following tables indicate the extent to which the laboratory Cytotechnologists/Pathologists at a
given site agreed amongst themselves on the diagnosis, comparing the Imager-assisted review to the
manual review. Tables are provided for ASC-US+ and ASC-H+. Note that since one site had only
two CT/Pathologist pairs, the three-way agreement analysis is available for just two sites, with 840
total specimens.
In Table 21 for ASC-H+, the number of specimens is shown for which various levels of agreement
among the CTs occurred. Either all three CTs rated the slide as positive (ASC-H+), two out of three
rated it positive, one out of three, or none of them.
Table 21: Laboratory Cytotechnologist/Pathologist Agreement, All Results, ASC-H+
ASC-H+
Imager-
Three CTs had
Assisted
ASC-H+
Review
Two CTs had ASC-H+
Three lab
and one had <ASC-H
CTs have
read the
One CT had ASC-H+
same slide
and two had <ASC-H
Three CTs had
<ASC-H
Totals
ASC-H+
Imager-
Assisted Three or two CTs had
Review ASC-H+
Three lab
CTs have Three or two CTs had
read the
<ASC-H
same slide
Totals
Manual Review
Three lab CTs have read the same slide
Two CTs had
Three CTs
ASC-H+
had
& one had
ASC-H+
<ASC-H
91 23
12 21
3 12
0 2
106 58
Manual Review
Three lab CTs have read the same slide
Three or two CTs
had ASC-H+
147
17
164
One CT had
Three
ASC-H+
CTs had
& two had
<ASC-H
<ASC-H
8 0
7 8
16 11
22 604
53 623
Three or two CTs
had <ASC-H
23
653
676
MAN-08723-001 Rev. 001 page 20 of 28
Totals
122
48
42
628
840
Totals
170
670
840