Ventilation Precautions; Environmental Precautions - AB Sciex QTRAP 4500 LC/MS/MS system System User's Manual

Ventilation Precautions

The venting of fumes and disposal of waste must be in accordance with all federal, state,
provincial, and local health and safety regulations. Use the system indoors in a laboratory that
complies with the environmental conditions recommended in the Site Planning Guide for the
system.
The source exhaust system and roughing pump must be vented either to an external fume hood
or to an external exhaust system as recommended in the Site Planning Guide for the system.
WARNING! Asphyxiation Hazard: Take care to vent exhaust gases properly. The
vent tubing must be secured with clamps. The use of mass spectrometers without
adequate ventilation to outside air might constitute a health hazard. In addition,
certain procedures required during the operation of the mass spectrometer might
cause gases to be discharged into the exhaust stream. Under these conditions,
inadequate ventilation might result in serious injury.
WARNING! Toxic Chemical Hazard, Biohazard, Radiation Hazard: Make
sure that the mass spectrometer is connected to the local exhaust system
and ducted to control hazardous emissions. The system should only be
used in a well-ventilated laboratory environment in compliance with local
regulations and with appropriate air exchange for the work performed.
Some jurisdictions recommend 4 to 12 air changes per hour in
laboratories.
WARNING! Potential Toxic Chemical Hazard, Biohazard, Radiation
Hazard: Do not operate the mass spectrometer if the source exhaust drain
and roughing pump exhaust hoses are not properly connected to the
laboratory ventilation system. Perform a regular check of the exhaust
tubing to ensure that there are no leaks.

Environmental Precautions

Use qualified personnel for the installation of electrical mains, heating, ventilation, and plumbing
supplies and fixtures. Make sure that all installations follow local bylaws and biohazard
regulations. For more information about the required environmental conditions for the system,
refer to the Site Planning Guide.
DANGER! Explosion Hazard: Do not operate the system in an environment
containing explosive gases. The system is not designed for operation in an
explosive environment.
WARNING! Asphyxiation Hazard: Take care to vent exhaust gases properly. The
use of mass spectrometers without adequate ventilation to outside air might
constitute a health hazard. In addition, certain procedures required during the
operation of the mass spectrometer might cause gases to be discharged into the
exhaust stream. Under these conditions, inadequate ventilation might result in
serious injury.
System User Guide
RUO-IDV-05-0264-A
Operational Precautions and Limitations
4500 Series of Instruments
13 of 138