AB Sciex QTRAP 4500 LC/MS/MS system System User's Manual page 58

Operating Instructions — Acquisition Methods
Item Parameter
1 DP (Declustering
Potential)
1 CUR (Curtain
Gas)
1 GS1 (Gas 1)
1 GS2 (Gas 2)
1 TEM
(Temperature)
1 IS (Ion Transfer
Voltage)
4500 Series of Instruments
58 of 138
Parameter Use
Type
Compound The DP parameter controls the
voltage on the orifice, which controls
the ability to decluster ions between
the orifice and the skimmer (or for
systems with an IonDrive QJet
guide, between the orifice and
IonDrive QJet ion guide). It is used to
minimize the solvent clusters that
may remain on the sample ions after
they enter the vacuum chamber, and,
if required, to fragment ions. The
higher the voltage, the higher the
energy imparted to the ions. If the DP
parameter is too high, unwanted
fragmentation may occur.
Use the preset value and optimize for
the compound.
Source and The CUR parameter controls the gas
gas flow of the Curtain Gas™ interface.
The Curtain Gas interface is located
between the curtain plate and the
orifice. It assists in solvent
evaporation and prevents solvent
droplets from entering and
contaminating the ion optics. The gas
flow should be maintained as high as
possible without losing sensitivity.
Source and The GS1 parameter controls the
gas nebulizer gas. The nebulizer gas
helps generate small droplets of
sample flow and affects spray
stability and sensitivity.
Source and The GS2 parameter controls the
gas auxiliary, or turbo, gas. It is used to
help evaporate the solvent to
produce gas phase sample ions.
Source and The TEM parameter controls the
gas temperature of the turbo gas (GS2)
in the TurboIonSpray probe or the
temperature of the probe in the
heated nebulizer (or APCI) probe.
Source and For the PhotoSpray
gas IS parameter controls the voltage
that transfers the ions from the
primary ionization region towards the
curtain plate orifice.
Scan Type
All
®
ion
All
All
All
All
®
ion source, the All
System User Guide
RUO-IDV-05-0264-A