Humidity Indicator; Spot Code - Accumetrics VerifyNow User Manual

eptifibatide). Assay devices are individually sealed in foil pouches and may be used
until the expiration date printed on each kit box and on the foil pouch.
Each single-use assay device consists of a sample well, staging well, and four
detection wells (Figure 2-5). The instrument automatically draws whole blood into the
assay device from a sample collection tube in the sample well. It then heats the
blood to 37°C for a period of time specific to each assay, and proceeds with the
analysis of the blood in the detection wells.
Figure 2-5 Assay Device
Finger Grip
Spot
Code
The detection wells of an assay device contain a lyophilized preparation of human
fibrinogen-coated beads and platelet agonist. Fibrinogen-coated beads bind to
available platelet receptors in the blood sample. When the activated platelets are
exposed to the fibrinogen-coated beads, agglutination occurs in proportion to the
number of available platelet receptors. The instrument measures this agglutination as
an increase in light transmittance through the detection wells.
2.2.1

Humidity Indicator

Each assay device contains a humidity indicator and is labeled with a unique spot
code. If the assay device has degraded due to prolonged exposure to room air, a
color change of the humidity indicator will be observed. If the humidity indicator is
pink on both sides, the assay device should be discarded.
2.2.2

Spot Code

Each assay device is labeled with a spot code. Upon insertion of the assay device
into the assay device port, the instrument automatically scans the spot code and
determines which assay is being performed, whether the particular lot has been used
previously, and if the lot expiration date has been reached.
VerifyNow System User Manual
OVERVIEW OF SYSTEM COMPONENTS - 2
Sample or
WQC Tube
Sheath
Needle
Sample Well
Humidity
Indicator
Page 17
Staging
Well
Detection
Wells
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