Accumetrics VerifyNow User Manual page 111

Term Description
F1 The mixer frequency flag count parameter reported during
electronic quality control diagnostics. See electronic quality
control.
F2 The mixer frequency transitions (high to low) parameter reported
during electronic quality control diagnostics. See electronic quality
control.
Fibrinogen A soluble blood plasma protein which the enzyme thrombin
converts into fibrin during the blood-clotting process. The binding
of the activated platelet IIb/IIIa receptors to fibrinogen (and vWF)
results in the formation of platelet-platelet and platelet-matrix
adhesive interactions and the formation of a stable, larger platelet
aggregate.
glycoprotein Activation induces a conformational change in the platelet
(GP) IIb/IIIa glycoprotein IIb/IIIa receptors on the surface of platelets to an
receptor activated high-affinity binding site for fibrinogen and vWF. The
binding of the activated platelet IIb/IIIa receptors to fibrinogen
(and vWF) results in the formation of platelet-platelet and platelet-
matrix adhesive interactions and the formation of a stable, larger
platelet aggregate at the site of injury.
Humidity Part of the assay device. It is used to determine if the lyophilized
indicator reagent in the assay device has degraded after prolonged
exposure to room air.
Icon Icons are used to navigate through the steps in a test. Icons
display along the right side of the display screen and correspond
to an adjacent icon key.
Icon keys The four icon keys directly to the right of the display screen
correspond to the different icons displaying on the screen.
Selecting an icon key displays another screen or directs the
instrument to perform an action.
Inhibitor, GP IIb/IIIa inhibitors block platelet aggregation by preventing
glycoprotein fibrinogen and other adhesion molecules (vWF) from binding to
(GP) IIb/IIIa the IIb/IIIa integrin on platelets.
VerifyNow System User Manual Page 111
APPENDIX - 11
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