Accumetrics VerifyNow User Manual page 115

Term Description
PRU See P2Y12 reaction units.
ReoPro Abciximab (trade name ReoPro
inhibitor mainly used during and after coronary artery procedures
like angioplasty to prevent thrombus (blood clot) formation within
the coronary artery. Its mechanism of action is inhibition of the
glycoprotein IIb/IIIa complex.
Sample well An assay device has of a sample well. The instrument
automatically draws whole blood into the assay device from a
sample collection tube in the sample well.
Staging well An assay device has of a staging well. The instrument heats the
blood in the staging well (except for the Aspirin assay).
Spot code The spot code consists of printed black circles on the assay
device. It provides information about the assay device to
determine which assay is being performed and the assay device
lot number.
Thienopyridine Thienopyridines are a class of therapy that has significant
antiplatelet effect by inhibiting adenosine diphosphate (ADP)-
mediated platelet activation. Thienopyridines irreversibly inhibit
ADP binding to the P2Y12 receptor on the platelet surface.
Clopidogrel (trade name Plavix
thienopyridine.
Thromboxane A potent platelet agonist, thromboxane A2 is released by
A2 activated platelets and acts to cause vasoconstriction and amplify
the platelet recruitment by binding to thromboxane receptors on
the surface of circulating platelets.
TRAP See iso-TRAP.
V1 The maximum vacuum level parameter reported during electronic
quality control diagnostics. See electronic quality control.
V2 The maximum leak rate parameter reported during electronic
quality control diagnostics. See electronic quality control.
VerifyNow A platelet function test developed by Accumetrics. The VerifyNow
system is a whole blood, point-of-care assay, which consists of a
turbidimetric-based optical detection instrument, single-use assay
devices, and associated quality controls. The system was formerly
named Ultegra
VerifyNow System User Manual
®
) is a platelet aggregation
®
- clopidogrel bisulfate) is a
®
.
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